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TK is a 63 year old male with chronic kidney disease (Cr Cl = 29 mL/min/1.73m2) and gout. He experienced his last gout attack about 2 months ago. Today his toe is extremely painful, hot, red and swollen. At a walk-in clinic, he receives a prescription for naproxen 500 mg po bid for 5 days. TK’s other current medication is pravastatin 20 mg po hs. Following successful resolution of the acute episode, TK’s physician decides that he should initiate allopurinol. TK should be advised to:

Limit fluid intake.

Take medication on an empty stomach.

Use precautions to avoid photosensitivity.

Report any skin rash or itching to the physician.

Allopurinol is a medication commonly used to treat gout by lowering the amount of uric acid in the body. It is important for TK to be aware of any potential side effects of this medication, such as skin rash or itching, and to notify his physician if he experiences any of these symptoms. Options A, B, and C are not correct because limiting fluid intake is not necessary for allopurinol treatment, taking the medication on an empty stomach is not recommended, and precautions to avoid photosensitivity are not relevant in this case. The main focus should be on educating TK about potential side effects of allopurinol and the importance of reporting them to his physician.

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