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DC, a 57 year old female, receives a prescription for celecoxib 100 mg po bid for osteoarthritis in her knees and hands. DC's only current medication is acetaminophen 650 mg po tid prn for joint pain. She enjoys a glass of wine with dinner and is a non-smoker. DC is otherwise healthy. Which of the following best represents the pharmacist's assessment of DC's new therapy?

  1. DC should discontinue acetaminophen with celecoxib use.

  2. DC should discontinue her wine consumption with celecoxib use.

  3. DC requires concurrent cytoprotection with celecoxib use.

  4. DC has no current drug therapy problems.

The correct answer is: DC has no current drug therapy problems.

The pharmacist's assessment of DC's new therapy is that she has no current drug therapy problems. This is because she is a healthy individual who is currently only taking acetaminophen for pain relief and has no contraindications for using celecoxib. Option A is incorrect because there is no need for DC to discontinue acetaminophen since the two medications can be used together. Option B is also incorrect because while alcohol consumption may increase the risk of potential side effects with celecoxib, it is not necessary for DC to completely stop drinking wine. Option C is incorrect because concurrent cytoprotection is not required for DC as she is not at a higher risk of developing gastrointestinal complications with celecoxib use.