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The pharmacist fills a prescription for sumatriptan 100 mg tablets for a patient with migraine. Appropriate information to provide to the patient includes which of the following?

  1. If the sumatriptan does not relieve the headache within four hours, ergotamine may be used.

  2. If no relief is achieved in two hours, a dose of 200 mg should be taken.

  3. If the headache returns, a dose of 100 mg can be repeated two hours after the first dose.

  4. The maximum dosage of sumatriptan 100 mg in any 24 hour period is six tablets.

The correct answer is: If the headache returns, a dose of 100 mg can be repeated two hours after the first dose.

Sumatriptan is a medication commonly used to treat migraines. It works by narrowing blood vessels in the brain and reducing the release of certain substances that can cause pain and inflammation. It is important for patients to understand the appropriate dosage and timing of taking this medication to effectively manage their migraines. Option A is incorrect because ergotamine is not recommended to be used in combination with sumatriptan. Using both medications together can increase the risk of serious side effects. Option B is also incorrect because taking a higher dosage of sumatriptan does not necessarily lead to quicker relief and can increase the risk of side effects. Option D is incorrect because the maximum recommended dosage of sumatriptan 100 mg in a 24-hour period is two tablets, not six. Option C is the most appropriate answer. It is important to understand that if the headache returns, a second dose of