Pharmacy PEBC Practice Exam

Which of the following is a common side effect of corticosteroids?

1. Hair loss

2. Weight gain

3. Dizziness

4. Dry mouth

The correct answer is: Weight gain

Weight gain is a common side effect of corticosteroids due to several mechanisms. Corticosteroids, such as prednisone and hydrocortisone, can increase appetite, leading to higher caloric intake. They also influence the distribution of fat in the body, often causing fat to accumulate in the face, abdomen, and back of the neck, which is sometimes referred to as "moon facies" or "buffalo hump." Additionally, corticosteroids can cause fluid retention, contributing to an increase in weight. This side effect is particularly important for patients managing chronic conditions who may require long-term corticosteroid therapy. Monitoring weight and managing diet may be necessary to mitigate this effect. Understanding the implications of weight gain can help healthcare providers counsel patients effectively about their treatment plans and monitor their health.