Pharmacy PEBC Practice Exam

Which of the following is a contraindication for aspirin use?

1. A history of hypertension

2. A history of diabetes

3. A history of allergic reactions to NSAIDs

4. A history of high cholesterol

The correct answer is: A history of allergic reactions to NSAIDs

Aspirin is classified as a non-steroidal anti-inflammatory drug (NSAID) and can cause allergic reactions in some individuals. A prior history of allergic reactions to NSAIDs is a significant contraindication for the use of aspirin since it suggests that the person may have an increased likelihood of experiencing similar allergic reactions to aspirin, potentially leading to serious complications such as anaphylaxis or other forms of hypersensitivity. In contrast, a history of hypertension, diabetes, or high cholesterol does not directly indicate that a patient should avoid aspirin. While these conditions may require careful consideration when prescribing any medication, including aspirin, they do not inherently preclude its use. Instead, these conditions may necessitate monitoring for potential risks associated with aspirin, such as gastrointestinal bleeding or cardiovascular effects, especially in patients with a history of cardiovascular disease.